Digital Twin Generators

Disease-specific models for generating patients’ digital twins

Our Digital Twin Generators (DTGs) are trained with extensive patient-level historical data to generate forecasts of individual disease progression under control or standard of care.

In addition to our validated DTGs, Unlearn enables sponsors to securely build and deploy custom DTGs using their proprietary data—entirely within their own secure environments and under their control. Deployment is flexible and scalable, available as a web-based application or a secure, on-premises solution within the sponsor’s cloud infrastructure.

Built to meet regulatory-grade compliance standards, including GxP, 21 CFR Part 11, and SOC 2 Type 2, Unlearn’s technology ensures sponsors maintain complete control over their systems, security, and data integrity.

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Alzheimer’s Disease (AD)

Alzheimer’s Disease Digital Twin Generator 4.1 (AD DTG 4.1)

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Amyotrophic Lateral Sclerosis (ALS)

Amyotrophic Lateral Sclerosis Digital Twin Generator 4.0 (ALS DTG 4.0)

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Frontotemporal Dementia (FTD)

Frontotemporal Dementia Digital Twin Generator 1.2 (FTD DTG 1.2)

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Huntington's Disease (HD)

Huntington's Disease Digital Twin Generator 1.2 (HD DTG 1.2)

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Parkinson's Disease (PD)

Parkinson's Disease Digital Twin Generator 1.2 (PD DTG 1.2)

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Crohn's Disease (CD)

Crohn's Disease Digital Twin Generator 1.1 (CD DTG 1.1)

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Rheumatoid Arthritis (RA)

Rheumatoid Arthritis Digital Twin Generator 1.0 (RA DTG 1.0)

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Atopic Dermatitis (ATD)

Atopic Dermatitis Digital Twin Generator 1.0 (ATD DTG 1.0)

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Psoriasis (PSO)

Psoriasis Digital Twin Generator 1.0 (PSO DTG 1.0)

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Stroke (STR)

Stroke Digital Twin Generator 1.1 (STR DTG 1.1)

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Type 2 Diabetes (T2D)

Type 2 Diabetes Digital Twin Generator 1.0 (T2D DTG 1.0)

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Dyslipidemia (DLD)

Dyslipidemia Digital Twin Generator 1.0 (DLD DTG 1.0)

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Hypertension (HTN)

Hypertension Digital Twin Generator 1.0 (HTN DTG 1.0)

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Major Depressive Disorder (MDD)

Major Depressive Disorder Digital Twin Generator 1.0 (MDD DTG 1.0)

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Neuroscience

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Alzheimer’s Disease (AD)

Alzheimer’s Disease Digital Twin Generator 4.1 (AD DTG 4.1)

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Amyotrophic Lateral Sclerosis (ALS)

Amyotrophic Lateral Sclerosis Digital Twin Generator 4.0 (ALS DTG 4.0)

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Frontotemporal Dementia (FTD)

Frontotemporal Dementia Digital Twin Generator 1.2 (FTD DTG 1.2)

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Huntington's Disease (HD)

Huntington's Disease Digital Twin Generator 1.2 (HD DTG 1.2)

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Parkinson's Disease (PD)

Parkinson's Disease Digital Twin Generator 1.2 (PD DTG 1.2)

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Immunology

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Crohn's Disease (CD)

Crohn's Disease Digital Twin Generator 1.1 (CD DTG 1.1)

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Rheumatoid Arthritis (RA)

Rheumatoid Arthritis Digital Twin Generator 1.0 (RA DTG 1.0)

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Atopic Dermatitis (ATD)

Atopic Dermatitis Digital Twin Generator 1.0 (ATD DTG 1.0)

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Psoriasis (PSO)

Psoriasis Digital Twin Generator 1.0 (PSO DTG 1.0)

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Cardio | Metabolic

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Stroke (STR)

Stroke Digital Twin Generator 1.1 (STR DTG 1.1)

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Type 2 Diabetes (T2D)

Type 2 Diabetes Digital Twin Generator 1.0 (T2D DTG 1.0)

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Dyslipidemia (DLD)

Dyslipidemia Digital Twin Generator 1.0 (DLD DTG 1.0)

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Hypertension (HTN)

Hypertension Digital Twin Generator 1.0 (HTN DTG 1.0)

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Musculoskeletal

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Psychiatric

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Major Depressive Disorder (MDD)

Major Depressive Disorder Digital Twin Generator 1.0 (MDD DTG 1.0)

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