AI-powered RCTs for the 21st century
AI-powered TwinRCTs reach full enrollment faster because they use smaller control groups than other trial designs
How it works
TwinRCTs leverage trial participants’ digital twins to enable highly powered studies with smaller control groups
Design an AI-powered trial
Our digital twin-generating AI models are trained on vast amounts of historical, individual-level data. By accounting for the information contained in these models, TwinRCTs are designed to provide more power with smaller control groups than other randomized trial designs.
Create AI-generated digital twins for every trial participant
The data collected from each participant at their first visit is input into the pre-trained AI model to generate their digital twins. These digital twins provide comprehensive, longitudinal predictions of every participant’s potential outcomes if they were to receive placebo and/or standard of care.
Use our regulatory-qualified framework to estimate the treatment effect
Each participant in a TwinRCT is randomized to a treatment or control group. At the end of the trial, information from the participants' digital twins is used to compute a precise, unbiased estimate of the treatment effect using our regulatory-qualified PROCOVA™ framework.
Highly powered clinical trials that reach full enrollment faster
AI-powered TwinRCTs hit enrollment targets faster because they require fewer participants to achieve the same power compared to traditional trial designs.
Attract trial participants
Many patients are wary of participating in clinical trials due to the prospect of receiving a placebo. TwinRCTs make control groups smaller, increasing a participant’s chance of receiving the experimental treatment.
Incorporating the comprehensive information from trial participants’ digital twins into trial analyses allows for more precise estimates of treatment effects at the population, subgroup, and even individual participant level.
For these indications and more
We are paving the regulatory pathway for AI-powered clinical research
Our partners leverage TwinRCTs to expedite clinical drug development
development with TwinRCTs
We partner with pharmaceutical and biotech companies to design AI-powered clinical trials that provide higher precision and shorter enrollment times.