TwinRCTs

Clinical trials powered by patients’ digital twins

How it works

Forecast

At the start of a trial, each participant has one of two potential outcomes:

one outcome if they are assigned to the treatment group or

one if they are assigned to the control group.

Their digital twin forecasts their potential control group outcome regardless of their actual assignment in the trial.

Participants’ digital twins are used in TwinRCTs, highly powered trials with smaller control groups.

Positioning TwinRCTs for regulatory success

Benefits

Traditional RCT
TwinRCT

Early stage studies

TwinRCTs improve the ability to observe treatment effects in early stage studies by increasing power without adding more patients.

Late stage studies

TwinRCTs reach full enrollment sooner because they require fewer patients to achieve the same power as traditional trial designs.